JFCR39

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JFCR39是日本癌研究會（Japanese Foundation for Cancer Research，JFCR）列出的39种人类癌症细胞系的列表[1]，用于抗癌药物筛选等科学研究[2]。与美国国家癌症研究所列出的NCI-60相比，JFCR39删去了所有白血病细胞系，但增加了胃癌细胞系，肺癌中不止列出非小细胞肺癌，也包括小细胞肺癌，还增加了几个来自日本病人的细胞系[1]。JFCR后续又设立了只包括胃癌、肝癌与乳腺癌三类的JFCR45[3]。

细胞系[编辑]

肺癌[编辑]

细胞系 类型 性别 倍增时间 也列入 文献 外部链接
NCI-H23 非小细胞肺癌 男 33.4h NCI-60 [4] CVCL_1547
NCI-H226 非小细胞肺癌 男 61h NCI-60 [4] CVCL_1544
NCI-H522 非小细胞肺癌 男 38.2h NCI-60 [4] CVCL_1567
NCI-H460 非小细胞肺癌 男 17.8h NCI-60 [4] CVCL_0459
A549 非小细胞肺癌 男 22.9h NCI-60 [5] CVCL_0023
DMS 273 小细胞肺癌 女 6.2 d [6] CVCL_1176
DMS 114 小细胞肺癌 男 27h NCI-60附加列表 [7] CVCL_1174

胃癌[编辑]

细胞系 性别 倍增时间 也列入 文献 外部链接
St-4 ？ ？ JFCR45 [8] CVCL_H265
MKN-1 男 43-45h JFCR45 [9] CVCL_1415
MKN-7 男 64-66h JFCR45 [10] CVCL_1417
MKN-28 男 28-32h JFCR45 [9] CVCL_1416
MKN-45 女 30-33 h JFCR45 [10] CVCL_0434
MKN-74 男 42-46h JFCR45 [10] CVCL_2791

卵巢癌[编辑]

细胞系 倍增时间 也列入 文献 外部链接
OVCAR-3 34.7h NCI-60 [11] CVCL_0465
OVCAR-4 41.4h NCI-60 [11] CVCL_1627
OVCAR-5 48.8h NCI-60 [11] CVCL_1628
OVCAR-8 26.1h NCI-60 [11] CVCL_1629
SK-OV-3 48.7h NCI-60 [12] CVCL_0532

肾癌[编辑]

细胞系 性别 倍增时间 也列入 文献 外部链接
RXF-631L ? ? [13] CVCL_A780
ACHN 男 27.5h NCI-60 [14] CVCL_1067

黑色素瘤[编辑]

细胞系 性别 倍增时间 也列入 文献 外部链接
LOX-IMVI 男 20.5h NCI-60 [15] CVCL_1381

结直肠癌[编辑]

细胞系 性别 倍增时间 也列入 文献 外部链接
HCC-2998 未知 31.5h NCI-60 [4] CVCL_1266
KM12 男 23.7h NCI-60 [13] CVCL_1331
HT-29 女 19.5h NCI-60 [16] CVCL_0320
HCT 15 男 20.6h NCI-60 [17] CVCL_0292
HCT 116 男 17.4h NCI-60 [18] CVCL_0291

乳腺癌[编辑]

细胞系 类型 倍增时间 也列入 文献 外部链接
HBC-4 ？ ？ JFCR45 [19] CVCL_B496
BSY-1 ？ ？ JFCR45 [19] CVCL_B499
HBC-5 ？ ？ JFCR45 [19] CVCL_B497
MCF-7 HR+ 25.4h JFCR45、ICBP43、NCI-60 [20] CVCL_0031
MDA-MB-231 三陰性乳癌 41.9h JFCR45、ICBP43、NCI-60 [21] CVCL_0062

脑癌[编辑]

细胞系 性别 倍增时间 也列入 文献 外部链接
U-251MG 男 23.8h NCI-60 [22] CVCL_0021
SF-268 女 33.1h NCI-60 [23] CVCL_1689
SF-295 女 29.5h NCI-60 [4] CVCL_1690
SF-539 女 35.4h NCI-60 [4] CVCL_1691
SNB-75 女 62.8h NCI-60 [24] CVCL_1706
SNB-78 男 50h [24] CVCL_B321

前列腺癌[编辑]

细胞系 性别 倍增时间 也列入 文献 外部链接
DU145 男 32.3h NCI-60 [25] CVCL_0105
PC-3 男 27.1h NCI-60 [26] CVCL_0035

JFCR45[编辑]

日本癌研究会后续又设立了细胞系列表JFCR45，包括21种胃癌细胞系，12种肝癌细胞系与12种乳腺癌细胞系[3][27]：

胃肠道癌
细胞系 类型 性别 年龄 文献 外部链接
GCIY 胃腺癌 女 39Y [28] CVCL_1228
GT3TKB 肺鳞状细胞癌 男 未知 [3] CVCL_1237
HGC27 胃癌 未知 未知 [29] CVCL_1279
AZ-521 十二指肠腺癌 男 53Y [30] CVCL_2862
4-1st 胃腺癌 女 51Y [31] CVCL_L498
NUGC-3 胃腺癌 72Y 男 [32] CVCL_1612
NUGC-3/5-FU 胃腺癌 72Y 男 [33] CVCL_L502
HSC-42 胃腺癌：横爬型癌 未知 未知 [34] CVCL_0316
AGS 胃腺癌 女 54Y [35] CVCL_0139
KWS-1 胃腺癌 男 42Y [36] CVCL_9816
TSG11 胃腺癌 女 46Y [3] CVCL_B477
OKIBA 胃腺癌 男 52Y [2] CVCL_L499
ISt-1 胃癌 男 63Y [37] CVCL_F645
ALF 胃癌 未知 未知 [3] CVCL_M035
AOTO 胃腺癌 男 69Y [2] CVCL_L501
肝癌
细胞系 文献 外部链接
Hep G2（英语：Hep G2） [38] CVCL_0027
Hep 3B [38] CVCL_0326
Li-7 [39] CVCL_3840
PLC/PRF/5 [40] CVCL_0485
Huh7 [41] CVCL_0336
HLE [42] CVCL_1281
HLF [42] CVCL_2947
Huh6 [43] CVCL_4381
REB [44] CVCL_4896
SSP-25 [44] CVCL_4902
HuL-1 [45] CVCL_8357
JHH-1 [46] CVCL_2785
乳腺癌
细胞系 文献 外部链接
KPL-3C [47] CVCL_E122
KPL-4 [48] CVCL_5310
KPL-1 [49] CVCL_2094
T-47D [50] CVCL_0553
HBC-9 [3] CVCL_L497
ZR-75-1 [51] CVCL_0588
HBC-8 [3] CVCL_L496

另见[编辑]

参考文献[编辑]

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