庚酸雄甾醇酮

**庚酸雄甾醇酮**
臨床資料
商品名（英语：Drug nomenclature）	Anaboleen Depot
其他名稱	Stanolone enanthate; Dihydrotestosterone enanthate; DHT enanthate; Dihydrotestosterone heptanoate; DHTH; 5α-Androstan-17β-ol-3-one 17β-heptanoate
给药途径	Intramuscular injection
藥物類別（英语：Drug class）	Androgen; Anabolic steroid; Androgen ester
识别信息
	IUPAC命名法 [(5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] heptanoate; ;
CAS号	33776-88-4
PubChem CID	160230;
ChemSpider	140831;
UNII	UAQ3N36A25;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID90955358 ;
化学信息
化学式	C26H42O3
摩尔质量	402.62 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES CCCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C;
	InChI InChI=1S/C26H42O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h18,20-23H,4-17H2,1-3H3/t18-,20-,21-,22-,23-,25-,26-/m0/s1; Key:DDYHAKNCTGGYOK-LVYWIKMTSA-N;

庚酸雄甾醇酮（英语：Androstanolone enanthate），也称为庚酸雄诺龙或庚酸二氢睾酮，是一种合成的雄激素和合成代谢类固醇和二氢睾酮酯。^[1]^[2]它用作注射剂，并作为雄甾醇酮（二氢睾酮）的前体药物。该药物已被研究并发现可有效治疗男孩和成年男性的男性乳房发育症。^[3]^[4]^[5]已对庚酸雄甾醇酮的药理学进行了研究。^[6]^[7]

参见[编辑]

雄激素酯列表

参考资料[编辑]

^ J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 640–. ISBN 978-1-4757-2085-3.
^ I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012: 261–. ISBN 978-94-011-4439-1.
^ Swerdloff, Ronald S.; Wang, Christina. Dihydrotestosterone: A rationale for its use as a non-aromatizable androgen replacement therapeutic agent. Baillière's Clinical Endocrinology and Metabolism. 1998, 12 (3): 501–506. ISSN 0950-351X. PMID 10332569. doi:10.1016/S0950-351X(98)80267-X.
^ Eberle AJ, Sparrow JT, Keenan BS. Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate. J. Pediatr. 1986, 109 (1): 144–9. PMID 3088241. doi:10.1016/s0022-3476(86)80596-0.
^ Swerdloff, Ronald S.; Dudley, Robert E.; Page, Stephanie T.; Wang, Christina; Salameh, Wael A. Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels. Endocrine Reviews. 2017, 38 (3): 220–254. ISSN 0163-769X. PMC 6459338 . PMID 28472278. doi:10.1210/er.2016-1067 .
^ Keenan, Bruce S.; Eberle, Andrea J.; Sparrow, James T.; Greger, Nancy G.; Panko, Walter B. Dihydrotestosterone Heptanoate: Synthesis, Pharmacokinetics, and Effects on Hypothalamic-Pituitary-Testicular Function. The Journal of Clinical Endocrinology & Metabolism. 1987, 64 (3): 557–562. ISSN 0021-972X. PMID 3546348. doi:10.1210/jcem-64-3-557.
^ Coutts SB, Kicman AT, Hurst DT, Cowan DA. Intramuscular administration of 5 alpha-dihydrotestosterone heptanoate: changes in urinary hormone profile. Clin. Chem. November 1997, 43 (11): 2091–8. PMID 9365393. doi:10.1093/clinchem/43.11.2091 .

[Elks2014-1] J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 640–. ISBN 978-1-4757-2085-3.

[MortonHall2012-2] I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012: 261–. ISBN 978-94-011-4439-1.

[SwerdloffWang1998-3] Swerdloff, Ronald S.; Wang, Christina. Dihydrotestosterone: A rationale for its use as a non-aromatizable androgen replacement therapeutic agent. Baillière's Clinical Endocrinology and Metabolism. 1998, 12 (3): 501–506. ISSN 0950-351X. PMID 10332569. doi:10.1016/S0950-351X(98)80267-X.

[pmid3088241-4] Eberle AJ, Sparrow JT, Keenan BS. Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate. J. Pediatr. 1986, 109 (1): 144–9. PMID 3088241. doi:10.1016/s0022-3476(86)80596-0.

[SwerdloffDudley2017-5] Swerdloff, Ronald S.; Dudley, Robert E.; Page, Stephanie T.; Wang, Christina; Salameh, Wael A. Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels. Endocrine Reviews. 2017, 38 (3): 220–254. ISSN 0163-769X. PMC 6459338 . PMID 28472278. doi:10.1210/er.2016-1067 .

[KeenanEberle1987-6] Keenan, Bruce S.; Eberle, Andrea J.; Sparrow, James T.; Greger, Nancy G.; Panko, Walter B. Dihydrotestosterone Heptanoate: Synthesis, Pharmacokinetics, and Effects on Hypothalamic-Pituitary-Testicular Function. The Journal of Clinical Endocrinology & Metabolism. 1987, 64 (3): 557–562. ISSN 0021-972X. PMID 3546348. doi:10.1210/jcem-64-3-557.

[pmid9365393-7] Coutts SB, Kicman AT, Hurst DT, Cowan DA. Intramuscular administration of 5 alpha-dihydrotestosterone heptanoate: changes in urinary hormone profile. Clin. Chem. November 1997, 43 (11): 2091–8. PMID 9365393. doi:10.1093/clinchem/43.11.2091 .

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