1,3,5-三甲氧基苯

1,3,5-三甲氧基苯
識別
CAS號	621-23-8
性質
化學式	C9H12O3
摩爾質量	168.19 g·mol−1
外觀	白色晶體
熔點	53—54 °C（326—327 K）
沸點	147 °C（420 K）（2.5 torr）
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

1,3,5-三甲氧基苯是一種有機化合物，化學式為C₉H₁₂O₃。它可由1,3,5-三溴苯和甲醇鈉在氯化亞銅、甲酸甲酯催化下反應製得。^[3]它和N-溴代丁二酰亞胺在四氯化碳中反應，可以得到2-溴-1,3,5-三甲氧基苯。^[4]它可用作核磁共振氫譜的內標。^[5]

參考文獻[編輯]

^ ^1.0 ^1.1 Qian Wang, Jian Yang, Yang Zheng, Xiali Liao. An Alternative Synthesis of 2,6-Dimethoxyl-1,4-Benzoquinone. Journal of Chemical Research. 2017-04, 41 (4): 193–194 [2023-04-03]. ISSN 1747-5198. doi:10.3184/174751917X14894997017379 （英語）.
^ Maillard, Jacques; Vincent, Michel; Delaunay, Pierre; Fumeron, Bernard. Derivatives of phloroglucinol. I. Synthesis and acetylation of mono-, di-, and triethers of mono- and dichloro-2,4,6-trihydroxybenzoic acid. Bulletin de la Societe Chimique de France, 1966. 8: 2520-2524.
^ Ying Guo, Si-Zhe Ji, Cheng Chen, Hong-Wei Liu, Jian-Hong Zhao, Yu-Lin Zheng, Ya-Fei Ji. A ligand-free, powerful, and practical method for methoxylation of unactivated aryl bromides by use of the CuCl/HCOOMe/MeONa/MeOH system. Research on Chemical Intermediates. 2015-11, 41 (11): 8651–8664 [2023-04-03]. ISSN 0922-6168. doi:10.1007/s11164-014-1917-x （英語）.
^ Mukulesh Mondal, Vedavati G. Puranik, Narshinha P. Argade. Facile Synthesis of 1,3,7-Trihydroxyxanthone and Its Regioselective Coupling Reactions with Prenal: Simple and Efficient Access to Osajaxanthone and Nigrolineaxanthone F. The Journal of Organic Chemistry. 2006-06-01, 71 (13): 4992–4995 [2023-04-03]. ISSN 0022-3263. doi:10.1021/jo0606655. （原始內容存檔於2021-06-12）（英語）.
^ Ruslan Muhamadejev, Renate Melngaile, Paula Paegle, Ieva Zibarte, Marina Petrova, Kristaps Jaudzems, Janis Veliks. Residual Solvent Signal of CDCl 3 as a qNMR Internal Standard for Application in Organic Chemistry Laboratory. The Journal of Organic Chemistry. 2021-03-05, 86 (5): 3890–3896 [2023-04-03]. ISSN 0022-3263. doi:10.1021/acs.joc.0c02744. （原始內容存檔於2021-11-19）（英語）.

[Wang-1] 1.0 ^1.1 Qian Wang, Jian Yang, Yang Zheng, Xiali Liao. An Alternative Synthesis of 2,6-Dimethoxyl-1,4-Benzoquinone. Journal of Chemical Research. 2017-04, 41 (4): 193–194 [2023-04-03]. ISSN 1747-5198. doi:10.3184/174751917X14894997017379 （英語）.

[2] Maillard, Jacques; Vincent, Michel; Delaunay, Pierre; Fumeron, Bernard. Derivatives of phloroglucinol. I. Synthesis and acetylation of mono-, di-, and triethers of mono- and dichloro-2,4,6-trihydroxybenzoic acid. Bulletin de la Societe Chimique de France, 1966. 8: 2520-2524.

[3] Ying Guo, Si-Zhe Ji, Cheng Chen, Hong-Wei Liu, Jian-Hong Zhao, Yu-Lin Zheng, Ya-Fei Ji. A ligand-free, powerful, and practical method for methoxylation of unactivated aryl bromides by use of the CuCl/HCOOMe/MeONa/MeOH system. Research on Chemical Intermediates. 2015-11, 41 (11): 8651–8664 [2023-04-03]. ISSN 0922-6168. doi:10.1007/s11164-014-1917-x （英語）.

[4] Mukulesh Mondal, Vedavati G. Puranik, Narshinha P. Argade. Facile Synthesis of 1,3,7-Trihydroxyxanthone and Its Regioselective Coupling Reactions with Prenal: Simple and Efficient Access to Osajaxanthone and Nigrolineaxanthone F. The Journal of Organic Chemistry. 2006-06-01, 71 (13): 4992–4995 [2023-04-03]. ISSN 0022-3263. doi:10.1021/jo0606655. （原始內容存檔於2021-06-12）（英語）.

[5] Ruslan Muhamadejev, Renate Melngaile, Paula Paegle, Ieva Zibarte, Marina Petrova, Kristaps Jaudzems, Janis Veliks. Residual Solvent Signal of CDCl 3 as a qNMR Internal Standard for Application in Organic Chemistry Laboratory. The Journal of Organic Chemistry. 2021-03-05, 86 (5): 3890–3896 [2023-04-03]. ISSN 0022-3263. doi:10.1021/acs.joc.0c02744. （原始內容存檔於2021-11-19）（英語）.

[1]

[2]

[3]

[4]

[5]